2424-92-2 EICOSANEDIOIC ACIID

Dabiiciga Dabiiciga ah: EICOSANEDIOIC ACID waxay u adeegtaa sidii dhex dhexaad muhiim u ah isku dhafka organic, ka qayb qaadashada isku dhafka isku dhafka dabiiciga ah ee kala duwan.Qaab dhismeedkeeda silsiladda alkyl waxa uu ka dhigayaa doorasho ku habboon in la soo saaro noocyo gaar ah oo unugyo ah.

Conjugates Antibody-Drug Conjugates (ADCs) Synthesis: EICOSANEDIOIC ACID waa xiriiriye aan la kala sooci karin oo loo isticmaalo isku dhafka dawada lidka ku ah (ADCs).ADCs waa dawooyin isku xira unugyada difaaca jirka iyo wakiilada cytotoxic, ujeedadoodu tahay in ay si sax ah u gaarsiiso wakiilka cytotoxic unugyada burooyinka iyada oo loo marayo aqoonsiga gaarka ah ee unugyada difaaca jirka, si loo gaaro saameyn hufan oo gaar ah antitumor.

PROTAC Synthesis: EICOSANEDIOIC ACID sidoo kale waa xiriiriye PROTAC oo ku saleysan silsilad alkyl, oo loo isticmaalo isku dhafka PROTACs.PROTACs waa unugyo isticmaala nidaamka ubiquitin-proteasome ee unugyada intracellular si ay si xushmad leh u yareeyaan borotiinnada bartilmaameedka ah.Adigoo isku xiraya laba qaybood oo kala duwan (mid loogu talagalay E3 ubiquitin ligase iyo kan kale ee borotiinka bartilmaameedka ah), PROTACs waxay awood u yeelaan hoos u dhigista borotiinnada bartilmaameedka ah, iyagoo door muhiim ah ka ciyaara daaweynta cudurka.