Shiinaha 2013-12-9 D(-)-Saaraha iyo Warshada Norvaline |Jiayinglai

2013-12-9 D(-)Norvaline

Sharaxaad Gaaban:

Muuqashada	Cadaan ilaa cad-cad
MF	C5H11NO2
MW	117.15
daahirnimo	98+

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Faahfaahinta Alaabta

Xaaladda gaadiidka&habka rarida ee lagu taliyay:
hawo, bad ama express

Xaaladda kaydinta:
2-8°C

Dalabka ugu Yar:
Gorgortanka

shahaado:
COA, HPLC, GC, HNMR, Assay, Content Water(KF), TLC diyaar ah

La mid ah

HD-NVA-OH;

HD-NHCH[CH3 (CH2)2] -COOH;

HD-NORVALINE;

HD-APE(2)-OH;

D-NVal-OH;

HD-2-AMINOVALERIC AID;

D-Nva-OH;

D-Nval

Baakad gudaha ah

Caadi ahaan waxaa loo isticmaalaa in lagu xidho budada.Waxayna ka hortagi karaan qorraxda iyo biyaha inay xumaadaan.

xirxirida dibadda

Kartoonka adag wuxuu ka ilaalin karaa alaabtaada inay shilmaan oo ay qoyaan.

Codsiyada

Waxaa loo isticmaali karaa in lagu sameeyo D-Glu.D-aminoacids kala duwan, sida D-serine, D-aspartic acid (D-Asp), iyo D-glutamicacid (D-Glu) ayaa si weyn looga helaa naasleyda oo ay ku jiraan bini'aadamka, waxaana hadda loo maleynayaa inay yihiin musharaxiinta jimicsiga jireed ee cusub. walxaha iyo/ama biomarkers.D-[Asp/Glu](4mg/mL) waxay ka hortagtaa ku xidhka IgE (75%) lawska halka D-Glu, D-Asp aanay lahayn wax saamayn ah oo ka hortag ah.IgE waxay gaar u tahay D-[Asp/Glu] waxaana laga yaabaa inay awood u yeelato inay meesha ka saarto IgE ama yaraynta IgE ee ku xidhan xasaasiyadaha lawska.

D-glutamicacid hadda waxaa la siiyaa fiiro gaar ah sida modulator ah gudbinta neerfaha iyo dheecaanka hoormoonka.Waxaa metabolized kaliya D-aspartate oxidase ee naasleyda.Ka dib duritaanka intraperitoneal, L-glutamate waxaa lagu gartaa a-ketoglutarate, halka D-glutamate loo beddelo n-pyrrolidone carboxylic acid.Kaarboon2 ee labada D- iyo L-glutamate waxa lagu beddelaa cecum-ka methyl carbon ee acetate.Beerka jiirka iyo kelyaha labaduba waxay kiciyaan beddelka D-glutamicacid ee n-pyrrolidone karboksilic acid.

alaabta la xidhiidha

L-NVal-OH	Fmoc-N-Me-L-Nval-OH
Fmoc-D-NvaL-OH	Boc-NVal-OH
Boc-D-NVal-OH	Boc-D-NVal-DCHA

Sarraynta

1. Adeegga R&D waa la heli karaa
2. Soo saaraha shahaadada ISO, dammaanad tayo leh
3.Koorsada buuxda ee adeegga dabagalka inta lagu jiro wax soo saarka
4.High kharash waxtar leh
5. Dukumentiyada shahaadaynta tayada leh ee la bixiyay codsi kasta oo macmiil ah
6.Great adeegga iibka ka dib, ilaalinta xiriirka dhow ee macaamiisha
7.Khayraadka buuxa si uu u caawiyo dhimista kharashka maraakiibta
8.Muunad bilaash ah oo la bixiyo si loo hubiyo tayada ka hor lacag bixin kasta
9.Payment term gorgortanka
10.Assit macaamiisha wax ka qabtaan arrimaha Shiinaha