Shiinaha 1799443-50-7 Fmoc-N-Me-D-Tyr(tBu)-Saaraha iyo Warshada OH |Jiayinglai

1799443-50-7 Fmoc-N-Me-D-Tyr(tBu)-OH

Sharaxaad Gaaban:

Muuqashada	budo cad-cad
MF	C29H31NO5
MW	473.56
daahirnimo	98+

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Nolosha shelf
Ilaa 2 sano

Dalabka ugu Yar:
1kg (gorgortanka)

shahaado:COA, barta dhalaalka, SpecificRotation [α]_D²⁰

Waxaan kuu soo diri doonaa xog kasta oo aad rabto.Waxaad arki kartaa xogta ka hor tixraac ahaan.

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La mid ah

(R) -2-((( (9H-Fluoren-9-yl) methoxy) carbonyl) (methyl) amino) -3- (4- (tert-butoxy) phenyl) propanoicacid;

(9H-Fluoren-9-yl)MethOxy] CarbonylN-Me-D-Tyr(tBu)-OH;

(2R)-3-[4- (tert-butoxy) phenyl] -2-({[(9H-fluoren-9-yl) methoxy] karbonyl} (methyl) amino) propanoicacid;

(2R) -2- [9H-fluoren-9-ylmethoxycarbonyl (methyl) amino] -3-[4-[(2-methylpropan-2-yl) oxy] phenyl] propanoicacid;

N-Fmoc-N-methyl-O-tert-butyl-D-tyrosine;

D-Tyrosine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy) karbonyl]-N-methyl-

Baakad gudaha ah

Inta badan waxaa loo isticmaalaa baakadaha budada.Waxay kuxirantahay shuruudaha macaamiishaSidaa darteed, noo sheeg dalabkaaga ka hor intaadan xirin haddii aad hayso codsiyo gaar ah.

xirxirida dibadda

1kg ilaa 25kg Baakaynta dibadda waa adag tahay.Way adag tahay in la gooyo oo la dhaawaco.Waxay si fiican u ilaalin kartaa alaabtaada.

Codsiyada

Fmoc-N-Me-D-Tyr (TBu) -OH, oo sidoo kale loo yaqaan N-α-(9-fluorenylmethoxycarbonyl) -N-α-methyl-D-tyrosine tert-butyl ester, waa soosaar amino acid ah oo la ilaaliyo inta badan la isticmaalo in synthesis peptide-waji adag.Xaruntani waxay isku daraysaa kooxda ilaalinta Fmoc ee terminus amino iyo tert-butyl (TBu) ester ilaalinaya kooxda phenolic hydroxyl ee D-tyrosine.

Kooxda Fmoc, sida hore loo soo sheegay, waa mid deggan oo ku milma dareerayaasha organic, taas oo ka dhigaysa mid ku habboon isku dhafka peptide.Si fudud ayaa looga saari karaa xaaladaha alkaline, taas oo u oggolaanaysa isku xirka isku xigxiga ee peptides ee taageerooyinka adag.Tert-butyl ester, dhanka kale, wuxuu ilaaliyaa kooxda phenolic hydroxyl ee D-tyrosine, hubinta xasilloonida iyo nadiifnimada inta lagu jiro habka isku-dhafka.

Codsiga aasaasiga ah ee Fmoc-N-Me-D-Tyr(TBu) -OH waxay ku jirtaa diyaarinta peptides ka kooban D-tyrosine.Isticmaalka soo-saarista amino acid-kan, cilmi-baarayaashu waxay soo bandhigi karaan D-tyrosine oo ay la socdaan labada amino iyo kooxaha phenolic hydroxyl ee lagu ilaaliyo isku xigxiga peptide-kooda.Tani waxay siinaysaa kontoroolka saxda ah ee qaab dhismeedka peptide waxayna fududaynaysaa soo bandhigida asiidhyada amino-yada kale iyo wax ka bedelka meelo gaar ah oo ku dhex jira silsiladda peptide.

D-Tyrosine waa amino acid-dabiiciga ah oo lagu dari karo peptides si loo barto sifooyinkooda bayooloji ama si loo abuuro analogs peptide oo leh waxqabadyo wax laga beddelay.Peptides ka kooban D-tyrosine waxa laga yaabaa inay lahaadaan hawlo bayooloji oo kala duwan marka la barbar dhigo dhiggooda L-tyrosine, taas oo ay ugu wacan tahay kala duwanaanshaha stereochemical ee u dhexeeya labada amino acids.

alaabta la xidhiidha

N-Me-Tyr(Aniga)-OH.HCl	Boc-N-Me-L-Tyr(tbu)-OH	Fmoc-N-Me-L-Tyr(tBu)-OH	Cbz-N-Me-Tyr(tbu)-OH
FMOC-N-Me-D-Tyr(aniga)-OH	Boc-N-Me-L-Tyr(bzl)-OH	Fmoc-N-Me-L-Tyr(bzl)-OH	Boc-N-Me-D-Tyr(bzl)-OH

Maxaa Nooga Doortay

1. Ku saabsan MOQ-ga: Waxaan ku hagaajin karnaa si waafaqsan shuruudahaaga.
2. Ku saabsan muunada: Muunadu waxay u baahan tahay kharashka muunada, taas oo noqon karta xamuul si loo qaado ama aad horay noogu sii bixin karto.
3. Aqoon-is-weydaarsiga caaryada, waxaa loo habeyn karaa iyadoo loo eegayo tirada moodooyinka.
4. Waxaan bixinaa adeegga ugu fiican.Koox iib ah oo khibrad leh ayaa horeyba kuugu shaqeyneysay.
5. Ku saabsan wax-is-weydaarsiga: Fadlan ii-mayl u dir ama ila sheekee marka ay kugu habboon tahay.

Hore: Cbz-N-Me-Tyr(tbu)-OH

Xiga: 428868-52-4 Fmoc-N-Me-L-Tyr(bzl)-OH

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