66638-37-7 Boc-N-Me-L-Tyr(tbu)-OH

Synthesis Peptide:
Boc-N-Me-L-Tyr(Tbu)-OH waa amino acid la ilaaliyo oo caadi ahaan loo isticmaalo isku-dhafka peptide-wajiga adag (SPPS) iyo hababka kale ee peptide synthesis.Iyada oo labada N-terminal iyo kooxaha hydroxyl-side-silsiladda la ilaaliyo, waxay ilaalisaa xasilloonida inta lagu jiro fidinta silsiladda peptide, ka fogaanshaha falcelinta aan loo baahnayn.
Ka dib marka la dhammeeyo isku-dhafka silsiladda peptide-ka, kooxaha ilaalinta ayaa laga saari karaa xaaladaha ku habboon, iyagoo soo bandhigaya kooxaha amino iyo hydroxyl ee bilaashka ah, taas oo keeneysa peptide ama borotiinka la rabo.
Injineeriyada borotiinka:
Injineernimada borotiinka, amino acid-kan la ilaaliyo waxa loo isticmaali karaa wax ka beddelka goobta gaarka ah ee borotiinada.Adigoo ka falcelinaya Boc-N-Me-L-Tyr(Tbu)-OH oo leh goobo gaar ah oo borotiin ah, haraaga tyrosine-ka methylated ayaa la soo bandhigi karaa, taasoo beddeleysa sifooyinka borotiinka iyo shaqada.
Nakhshadeynta iyo Horumarinta Dawada:
Methylated tyrosine waxaa laga yaabaa inay soo bandhigto waxqabadyo bayooloji gaar ah ama guryaha farmashiyaha ee nashqadaha daawooyinka qaarkood.Adigoo isticmaalaya Boc-N-Me-L-Tyr(Tbu)-OH dhisme ahaan, cilmi-baarayaashu waxay sahamin karaan waxtarka daweynta ee suurtogalka ah iyo sifooyinka dawooyinka ee molecules daroogada ay ku jiraan tyrosine methylated.
Baadhista Kiimikaalka iyo Bayoloji:
Cilmi-baarista bayoolojiga iyo bayoolajiga, amino acid-kan la ilaaliyo wuxuu u adeegi karaa qalab ka kooban si uu u barto doorka methylated tyrosine ee isdhexgalka borotiinka, gudbinta calaamadaha, dhaqdhaqaaqa enzyme, iyo dhinacyo kale.
Bioconjugation iyo calaamadaynta:
methyl iyo kooxaha hydroxyl ee la ilaaliyo ee Boc-N-Me-L-Tyr(Tbu) -OH waxay ka dhigaan doorasho ku habboon bioconjugation iyo falcelinta calaamadaynta.Adiga oo meesha ka saaraya kooxaha ilaalinaya oo ka falcelinaya molecules kale ama walxaha noolaha firfircoon, molecules calaamadeysan oo leh hawlo bayooloji gaar ah ayaa la diyaarin karaa.