Shiinaha 66638-37-7 Boc-N-Me-L-Tyr(tbu)-Saaraha iyo Warshada OH |Jiayinglai

66638-37-7 Boc-N-Me-L-Tyr(tbu)-OH

Sharaxaad Gaaban:

Muuqashada	budo cad-cad
MF	C19H29NO5
MW	351.44
daahirnimo	98+

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Nolosha shelf
Ilaa 2 sano

Dalabka ugu Yar:
1kg (gorgortanka)

shahaadoCOA, barta dhalaalka, SpecificRotation [α]_D²⁰

Waxaan kuu soo diri doonaa xog kasta oo aad rabto.Waxaad arki kartaa xogta ka hor tixraac ahaan.

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La mid ah

(Ter-Butoxy) CarbonylN-Me-Tyr(tBu)-OH;

(2R)-2-{[(tert-butoxy) karbonyl] (methyl) amino}-3-[4- (tert-butoxy) phenyl] propanoicacid;

Boc-L-MeTyr(tBu)-OH;

N-Boc-N-methyl-O-tert-butyl-L-tyrosine;

L-Tyrosine, N-[(1,1-dimethylethoxy) karbonyl] -O- (1,1-dimethylethyl) -N-methyl-;

N-α-(t-Butoxycarbonyl)-N-α-methyl-O- (t-butyl) -L-tyrosine;

(S)-3-(4- (tert-Butoxy) phenyl)-2-((tert-butoxycarbonyl) (methyl) amino) propanoicacid

Baakad gudaha ah

Inta badan waxaa loo isticmaalaa baakadaha budada.Waxay kuxirantahay shuruudaha macaamiishaSidaa darteed, noo sheeg dalabkaaga ka hor intaadan xirin haddii aad hayso codsiyo gaar ah.

xirxirida dibadda

1kg ilaa 25kg Baakaynta dibadda waa adag tahay.Way adag tahay in la gooyo oo la dhaawaco.Waxay si fiican u ilaalin kartaa alaabtaada.

Codsiyada

Synthesis Peptide:
Boc-N-Me-L-Tyr(Tbu)-OH waa amino acid la ilaaliyo oo caadi ahaan loo isticmaalo isku-dhafka peptide-wajiga adag (SPPS) iyo hababka kale ee peptide synthesis.Iyada oo labada N-terminal iyo kooxaha hydroxyl-side-silsiladda la ilaaliyo, waxay ilaalisaa xasilloonida inta lagu jiro fidinta silsiladda peptide, iyada oo ka fogaanaysa falcelinta dhinaca aan loo baahnayn.
Ka dib marka la dhammeeyo isku-dhafka silsiladda peptide-ka, kooxaha ilaalinta ayaa laga saari karaa xaaladaha ku habboon, iyagoo soo bandhigaya kooxaha amino iyo hydroxyl ee bilaashka ah, taas oo keeneysa peptide ama borotiinka la rabo.
Injineeriyada borotiinka:
Injineernimada borotiinka, amino acid-kan la ilaaliyo waxa loo isticmaali karaa wax ka beddelka goobta gaarka ah ee borotiinada.Adigoo ka falcelinaya Boc-N-Me-L-Tyr(Tbu)-OH oo leh goobo gaar ah oo borotiin ah, haraaga tyrosine-ka methylated ayaa la soo bandhigi karaa, taasoo beddeleysa sifooyinka borotiinka iyo shaqada.
Nakhshadeynta iyo Horumarinta Dawada:
Methylated tyrosine waxaa laga yaabaa inay soo bandhigto waxqabadyo bayooloji gaar ah ama guryaha farmashiyaha ee nashqadaha daawooyinka qaarkood.Adigoo isticmaalaya Boc-N-Me-L-Tyr(Tbu)-OH dhisme ahaan, cilmi-baarayaashu waxay sahamin karaan waxtarka daweynta ee suurtogalka ah iyo sifooyinka dawooyinka ee molecules daroogada ay ku jiraan tyrosine methylated.
Baadhista Kiimikaalka iyo Bayoloji:
Cilmi-baarista bayoolojiga iyo bayoolajiga, amino acid-kan la ilaaliyo wuxuu u adeegi karaa qalab ka kooban si uu u barto doorka methylated tyrosine ee isdhexgalka borotiinka, gudbinta calaamadaha, dhaqdhaqaaqa enzyme, iyo dhinacyo kale.
Bioconjugation iyo calaamadaynta:
methyl iyo kooxaha hydroxyl ee la ilaaliyo ee Boc-N-Me-L-Tyr(Tbu) -OH waxay ka dhigaan doorasho ku habboon bioconjugation iyo falcelinta calaamadaynta.Adiga oo meesha ka saaraya kooxaha ilaalinaya oo ka falcelinaya molecules kale ama walxaha noolaha firfircoon, molecules calaamadeysan oo leh hawlo bayooloji gaar ah ayaa la diyaarin karaa.

alaabta la xidhiidha

N-Me-Tyr(Aniga)-OH	FMOC-N-Me-D-Tyr(aniga)-OH	Fmoc-N-Me-L-Tyr(tBu)-OH	Cbz-N-Me-Tyr(tbu)-OH
Fmoc-N-Me-D-Tyr(tBu)-OH	Boc-N-Me-L-Tyr(bzl)-OH	Fmoc-N-Me-L-Tyr(bzl)-OH	Boc-N-Me-D-Tyr(bzl)-OH

Maxaa noo doora

1. Ku saabsan MOQ-ga: Waxaan ku hagaajin karnaa si waafaqsan shuruudahaaga.
2. Ku saabsan muunada: Muunadu waxay u baahan tahay kharashka muunada, taas oo noqon karta xamuul si loo qaado ama aad horay noogu sii bixin karto.
3. Aqoon-is-weydaarsiga caaryada, waxaa lagu habeyn karaa iyadoo loo eegayo tirada moodooyinka.
4. Waxaan bixinaa adeegga ugu fiican.Koox iib ah oo khibrad leh ayaa horeyba kuugu shaqeyneysay.
5. Ku saabsan wax-is-weydaarsiga: Fadlan ii-mayl u dir ama ila sheekee marka ay kugu habboon tahay.

Hore: 52939-33-0 N-Me-Tyr(aniga)-OH

Xiga: Cbz-N-Me-Tyr(tbu)-OH

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