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428868-52-4 Fmoc-N-Me-L-Tyr(bzl)-OH

428868-52-4 Fmoc-N-Me-L-Tyr(bzl)-OH

Sharaxaad Gaaban:

Muuqashada budo cad-cad
MF C32H29NO5
MW 507.58
daahirnimo 98+


Faahfaahinta Alaabta

Xaaladda gaadiidka
Waxay noqon kartaa heerkul caadi ah

Ku talin habka rarida
Hawada By Dhulka Badda

Xaaladda kaydinta:
Ku hay meel mugdi ah, jawi aan fiicneyn, heerkulka qolka

Nolosha shelf
Ilaa 2 sano

Dalabka ugu Yar:
1kg (gorgortanka)

shahaadoCOA, barta dhalaalka, SpecificRotation [α]D20                      

Waxaan kuu soo diri doonaa xog kasta oo aad rabto.Waxaad arki kartaa xogta ka hor tixraac ahaan.

Alaabta la habeeyey, waxaanu u dirnaa xogta ugu cusub ka dib markay soo baxaan.

D-Lys(tfa)-NCA (2)

La mid ah

FMOC-L-METYR(BZL)-OH;

FMOC-METYR(BZL)-OH;

FMOC-N-ALPHA-METHYL-O-BENZYL-L-TYROSINE;

FMOC-N-ME-TYR(BZL)-OH;

FMOC-N-METHYL-O-BENZYL-L-TYROSINE;

N-ALPHA-FMOC-N-ALPHA-METHYL-O-BENZYL-L-TYROSINE;

N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-ALPHA-METHYL-O-BENZYL-L-TYROSINE;

N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-ALPHA-METHYL-O-BENZYL-L-TYROSINE

Baakad gudaha ah

Inta badan waxaa loo isticmaalaa baakadaha budada.Waxay kuxirantahay shuruudaha macaamiishaSidaa darteed, noo sheeg dalabkaaga ka hor intaadan xirin haddii aad hayso codsiyo gaar ah.

Xirmooyinka gudaha 2
Xirmooyinka gudaha 1
Xirmooyinka gudaha 3

xirxirida dibadda

1kg ilaa 25kg Baakaynta dibadda waa adag tahay.Way adag tahay in la gooyo oo la dhaawaco.Waxay si fiican u ilaalin kartaa alaabtaada.

Xirmooyinka dibadda 3
Xirmooyinka dibadda 2
Xirmooyinka dibadda 1

Codsiyada

Fmoc-N-Me-L-Tyr (Bzl) -OH, oo sidoo kale loo yaqaan N-α-(9-fluorenylmethoxycarbonyl) -N-α-methyl-L-tyrosine benzyl ester, waa soosaar amino acid ah oo la ilaaliyo oo caadi ahaan loo isticmaalo si adag. -fase peptide synthesis.Xaruntani waxay isku daraysaa kooxda ilaalinta Fmoc ee terminus amino iyo benzyl (Bzl) ester ilaalinaya kooxda phenolic hydroxyl ee L-tyrosine.

Kooxda Fmoc waa mid aad u xasilloon oo ku milma dareerayaasha organic, taas oo ka dhigaysa mid ku habboon isku-darka peptide.Si fudud ayaa looga saari karaa xaaladaha alkaline, taas oo u oggolaanaysa isku xirka isku xigxiga ee peptides ee taageerooyinka adag.Ester-ka benzyl, dhanka kale, wuxuu ilaaliyaa kooxda phenolic hydroxyl ee L-tyrosine, ka hortagga falcelinta aan loo baahnayn inta lagu jiro habka isku-dhafka.

Codsiga aasaasiga ah ee Fmoc-N-Me-L-Tyr (Bzl) -OH waxay ku jirtaa diyaarinta peptides ka kooban L-tyrosine.Marka la soo bandhigo soo-saarkan amino acid ee isku xigxiga peptide, cilmi-baarayaashu waxay ku dari karaan L-tyrosine oo ay la socdaan kooxaha amino iyo phenolic hydroxyl labadaba.Tani waxay u oggolaaneysaa in si sax ah loo xakameeyo qaab-dhismeedka peptide-ka waxayna fududeyneysaa soo bandhigida asiidhyada amino-yada kale iyo wax ka beddelka meelo gaar ah oo ku dhex jira silsiladda peptide.

L-Tyrosine waa amino acid lagama maarmaan u ah nafaqeynta aadanaha waxayna leedahay hawlo bayooloji oo kala duwan, oo ay ku jiraan u adeegida horudhac u ah neurotransmitters iyo soosaarka melanin.Peptides ka kooban L-tyrosine waxa loo isticmaali karaa in lagu barto hawlahan ama lagu sameeyo dawooyin cusub ama dawooyin cusub.

alaabta la xidhiidha

N-Me-Tyr(Aniga)-OH.HCl Boc-N-Me-L-Tyr(tbu)-OH Fmoc-N-Me-L-Tyr(tBu)-OH Cbz-N-Me-Tyr(tbu)-OH
Fmoc-N-Me-D-Tyr(tBu)-OH Boc-N-Me-L-Tyr(bzl)-OH FMOC-N-Me-D-Tyr(aniga)-OH Boc-N-Me-D-Tyr(bzl)-OH

Maxaa noo doora

1. Ku saabsan MOQ-ga: Waxaan ku hagaajin karnaa si waafaqsan shuruudahaaga.
2. Ku saabsan muunada: Muunadu waxay u baahan tahay kharashka muunada, taas oo noqon karta xamuul si loo qaado ama aad horay noogu sii bixin karto.
3. Aqoon-is-weydaarsiga caaryada, waxaa lagu habeyn karaa iyadoo loo eegayo tirada moodooyinka.
4. Waxaan bixinaa adeegga ugu fiican.Koox iib ah oo khibrad leh ayaa horeyba kuugu shaqeyneysay.
5. Ku saabsan wax-is-weydaarsiga: Fadlan ii-mayl u dir ama ila sheekee marka ay kugu habboon tahay.


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