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51293-47-1 Boc-Ser (aniga) -OH

51293-47-1 Boc-Ser (aniga) -OH

Sharaxaad Gaaban:

Muuqashada Ydareere cawl ah si adag
MF C9H17NO5
MW 219.24
daahirnimo 95+


Faahfaahinta Alaabta

Xaaladda gaadiidka
Waxay noqon kartaa heerkul caadi ah

Ku talin habka rarida
Hawada By Dhulka Badda

Xaaladda kaydinta:
Ku hay meel mugdi ah, jawi aan fiicneyn, heerkulka qolka

Nolosha shelf
Ilaa 2 sano

Dalabka ugu Yar:
1kg (gorgortanka)

shahaadoCOA, barta dhalaalka, SpecificRotation [α]D20                      

Waxaan kuu soo diri doonaa xog kasta oo aad rabto.Waxaad arki kartaa xogta ka hor tixraac ahaan.

Alaabta la habeeyey, waxaanu u dirnaa xogta ugu cusub ka dib markay soo baxaan.

Dareeraha saliidda ah 1

La mid ah

(2S)-2-(tert-Butoxycarbonylamino) -3-methoxy-propanoicacid;
(S)-N-BOC-2-AMINO-3-METHOXY-PROPIONICACID;
N-ALPHA-T-BUTOXYCARBONYL-O-METHYL-L-serin;
N-ALPHA-T-BUTOXYCARBONYL-O-METHYL-LSERINEDICYCLOHEXYLAMMONIUMSALT;
N-ALPHA-T-BOC-O-METHYL-SERINE;
BOC-(S)-2-AMINO-3-METHOXYLPROPANOICACID;
BOC-(S)-2-AMINO-3-METHOXYPROPIONICACID

Baakad gudaha ah

Inta badan waxaa loo isticmaalaa baakadaha budada.Waxay kuxirantahay shuruudaha macaamiishaSidaa darteed, noo sheeg dalabkaaga ka hor intaadan xirin haddii aad hayso codsiyo gaar ah.

Xirmooyinka gudaha 2
Xirmooyinka gudaha 1
Xirmooyinka gudaha 3

xirxirida dibadda

Xirmooyinka dibadda ayaa adag.Way adag tahay in la gooyo oo la dhaawaco.Waxay si fiican u ilaalin kartaa alaabtaada.

Xirmooyinka dibadda 3
Xirmooyinka dibadda 2
Xirmooyinka dibadda 1

Codsiyada

Cilmi-baarista biochemical:
Boc-Ser (Aniga) -OH waxay u adeegtaa sidii reagen biochemical oo qiimo leh oo ku jira isku-dhafka borotiinka, falcelinta enzymatic, iyo daraasadaha isdhexgalka molecular.
Waxay ku dayan kartaa shaqada serine dabiiciga ah, samaynta silsilado peptide ah oo leh asiidhyada kale ee amino ama qaybaha peptide si ay u bixiso fikrado ku saabsan qaabka iyo shaqada borotiinka.
Helitaanka Dawada:
Boc-Ser(Aniga) -OH waxay door muhiim ah ka ciyaartaa helitaanka maandooriyaha sababtoo ah dhaqdhaqaaqeeda bayooloji.
Iyada oo loo marayo wax ka beddelka qaabdhismeedka iyo hagaajinta, waxay u adeegi kartaa musharraxa daroogada ama horudhaca daroogada ee horumarinta daweynta cusub.
Intaa waxaa dheer, waxaa loo isticmaali karaa isku-darka daawooyinka peptide-ku-saleysan ee leh waxqabadyo farmaajo ama dhexdhexaad ah isku-darka daroogada.
Isku-dhafka dabiiciga ah:
Isku-dhafka dabiiciga ah, Boc-Ser (Aniga) -OH waxay u adeegtaa sidii dhexdhexaadiyaha synthetic ee dhismaha molecules organic adag.
Kooxaha ilaalinta Boc iyo O-methyl ee qaab-dhismeedkeedu waxay u oggolaanayaan ilaalinta kooxo hawleed gaar ah, ka hortagga falcelinta dhinaca aan loo baahnayn inta lagu jiro habka synthetic.
Ka dib marka la dhammeeyo isku-dhafka, kooxahan ilaalinta ayaa si xushmad leh looga saari karaa si loo helo molecule bartilmaameedka la doonayo.
Synthesis Peptide:
Boc-Ser (Aniga) -OH waxaa caadi ahaan loo isticmaalaa sidii amino acid bilawga ah ee isku dhafka peptide-wejiga adag.
Si tartiib ah loogu daro haraaga amino acids kale, silsiladaha peptide ee leh qaabab iyo qaabab gaar ah ayaa la isku dhejin karaa.
Silsiladaan peptide-ka ah waxaa loo adeegsan karaa daraasadda xiriirka shaqada qaab-dhismeedka borotiinka, horumarinta dawooyinka cusub ee peptide-ku-saleysan, ama dib-u-heleyaasha ogaanshaha.

alaabta la xidhiidha

L-Ser H-DL-Ser-OH D-Ser-OH
L-Ser-Ol L-Ser-Ol L-Ser(Aniga)-OH
HL-Ser(Aniga)-OH.HCl DL-Ser (Aniga) -OH D-Ser (aniga)
HL-Ser(tBu)-OH D-Ser(tBu)-OH D-Ser(bzl)
D-Ser(bzl).HCl HL-Ser(Bzl)-OH.HCl HL-Ser(Bzl)-OH
HL-Ser(Bzl)-OL.HCl HL-Ser-OMe.HCl L-Ser-Oet.Hcl
HL-Ser-OBzl.HCl HL-Ser-OBzl DL-Ser-Obzl.Hcl
D-Ser-Obzl.Hcl Boc-L-Ser(Bzl)-OH Boc-DL-Ser(Bzl)-OH
Boc-Ser(Bzl)-ol Boc-D-Ser(Bzl)-OL Boc-L-Ser-OMe
Boc-L-Ser-Obzl Boc-L-Ser(cl)-OMe Fmoc-L-Ser(bzl)-OH
Fmoc-D-Ser(bzl)-OH Fmoc-N-Me-Ser(bzl) ZL-Ser(Bzl)-OH
Cbz-D-Ser(Bzl)-OH Cbz-L-Ser-Ome Cbz-DL-Ser-ome
Cbz-D-Ser-Ome Cbz-L-Ser-Obzl

adva

1. Ku saabsan wax-is-weydaarsiga: Fadlan iimayl ii soo dir ama ila hadal marka ay kugu habboon tahay.
2. Tayo sare leh: Isticmaalka walax tayo sare leh iyo samaynta nidaam adag oo lagu xakamaynayo tayada, iyada oo loo xilsaarayo dad gaar ah oo masuul ka ah geedi socod kasta oo wax soo saar ah, laga bilaabo iibsashada alaabta ceeriin ilaa xirmo.
3. Aqoon-is-weydaarsiga caaryada, qaabka la habeeyey ayaa loo samayn karaa iyadoo loo eegayo tirada.
4. Waxaan bixinaa adeegga ugu fiican sida aan haysano.Kooxda iibka ee khibradda leh ayaa mar horeba kuu shaqayn doona.


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