Shiinaha 40216-83-9 H-Hyp-Ome·Saaraha iyo Warshada HCl |Jiayinglai

40216-83-9 H-Hyp-Ome·HCl

Sharaxaad Gaaban:

Muuqashada	Budada cad
MF	C6H12ClNO3
MW	181.62
daahirnimo	98+

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Hawada By Dhulka Badda

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Nolosha shelf
Ilaa 2 sano

Dalabka ugu Yar:
1kg (gorgortanka)

shahaadoCOA, barta dhalaalka, SpecificRotation [α]_D²⁰

Waxaan kuu soo diri doonaa xog kasta oo aad rabto.Waxaad arki kartaa xogta ka hor tixraac ahaan.

Alaabta la habeeyey, waxaanu u dirnaa xogta ugu cusub ka dib markay soo baxaan.

La mid ah

H-HYP-OMEHCL;
HL-HYP-OMEHCL;
HYDROXYPROLINE-OMEHCL;
(2S,4R)-trans-4-hydroxy-L-prolinemethylesterhydrochloride;
4-hydroxy-2-pyrrolidinecarboxylicacidmethylesterhydrochloride;
L-4-HYDROXYPROLINEMETHYLESTERHYDROCLORIDE;
L-4-HYDROXYPROLINEMETHYLESTERHYDROCLORIDESALAT;
L-4-Trans-HYDROXYPROLINEMETHYLESTERHYDROCLORIDE

Baakad gudaha ah

Inta badan waxaa loo isticmaalaa baakadaha budada.Waxay kuxirantahay shuruudaha macaamiishaSidaa darteed, noo sheeg dalabkaaga ka hor intaadan xirin haddii aad hayso codsiyo gaar ah.

xirxirida dibadda

1kg ilaa 25kg Baakaynta dibadda waa adag tahay.Way adag tahay in la gooyo oo la dhaawaco.Waxay si fiican u ilaalin kartaa alaabtaada.

Codsiyada

Waxay isticmaashaa: H-Hyp-OMe·HCl waxay u adeegtaa sidii isku xidhaha ADC-da aan la furfuri karin (ka-hortagga-daawoyinka)ADCs, oo ka kooban antibody iyo cytotoxin ku xiran iyada oo loo sii marayo xiriiriyaha ADC, waxay awood u siineysaa si sax ah u bixinta cytotoxins si ay u beegsato unugyada, taas oo lagu daweynayo cudurro gaar ah.Intaa waxaa dheer, H-Hyp-OMe·HCl waa PROTAC (hoos u dhaca borotiinka ee lagu beegsanayo chimera) isku xidhaha ku salaysan silsiladaha alkyl, ee loo isticmaalo isku dhafka PROTACs.PROTACs, kuwaas oo ka kooban laba qaybood oo kala duwan oo ay ku xiran yihiin xiriiriye, waxay isticmaalaan nidaamka ubiquitin-proteasome-ka gacanta si ay si xushmad leh u yareeyaan borotiinnada bartilmaameedka ah.

Guryaha: H-Hyp-OMe·HCl waa budo amorphous ah oo cad ama waxoogaa huruud ah oo ku milma dareerayaasha sida biyaha, methanol, iyo ethanol.Waxay soo bandhigtaa xasillooni wanaagsan iyo is-qabsi noole, ilaalinaysa dhaqdhaqaaqeeda iyo xasilloonida xaaladaha jireed.

Guud ahaan, H-Hyp-OMe·HCl waxa ay door muhiim ah ka ciyaartaa isku dhafka ADC-yada iyo PROTACs sida reagen biochemical oo muhiim ah iyo qalab horumarinta daroogada.Waxay bixisaa wadooyin iyo habab cusub oo loogu talagalay daaweynta cudurrada.Marka cilmi-baaristu sii socoto iyo tignoolajiyadu horumarto, rajada codsiga ee H-Hyp-OMe·HCl ayaa la filayaa inay ballaarato.

alaabta la xidhiidha

L-Hyp-OH	HL-Hyp-Ome·HCl
HL-Hyp-Oet.HCl	L-Hyp-Obzl.Hcl
Boc-L-Hyp-OH	Boc-L-Hyp-Ome
Fmoc-L-Hyp-Ome	Boc-L-Hyp-oet
Fmoc-L-Hyp-OH	Fmoc-L-Hyp(tbu)-OH
Cbz-L-Hyp-OH	Cbz-L-Hyp-OMe

Sarraynta

1. Waxaanu ku siinaynaa habaynta alaabta aad u baahan tahay.
2. Tayo sare leh & qiimo tartan ah ayaa la bixin karaa.
3. Waxa aanu kuu balan qaadaynaa adeeg dabagal oo dhamaystiran.
4. Su'aalaha alaab-qeybiyaha iyo dukumentiyada farsamada waa la bixin karaa haddii la codsado ka dib marka la buuxiyo qadar go'an.
5. Adeegga iibka ka dib ama dammaanad qaadka weyn: Su'aashaada mid kasta ayaa lagu xallin doonaa sida ugu dhakhsaha badan.
6. Dhoofinta badeecadaha tartanka ku jira, sannad kastana tiro badan oo dibadda ah loo dhoofiyo.
7. Muunad bilaash ah oo la bixiyo si loo hubiyo tayada ka hor lacag bixin kasta.

Hore: 33208-99-0 L-Ala-NH2.HCl

Xiga: 7362-93-8 H-Asp-OBzl

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