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1809273-81-1 D-Lys(tfa)-NCA

1809273-81-1 D-Lys(tfa)-NCA

Sharaxaad Gaaban:

Muuqashada Budada cad
MF C9H11F3N2O4
MW 268.19
daahirnimo 98+


Faahfaahinta Alaabta

Xaaladda gaadiidka&ku taliyaan habka dhoofinta
Gaadiidka silsiladda qabow (-18℃~-20℃)
hawo

Xaaladda kaydinta:
qaboojiyaha (-18 ~ -30 ℃)
Madow qalalan
shaabadeeyey

Dalabka ugu Yar
10gm

shahaadoCOA, HPLC, GC, HNMR, Assay, Content Water(KF), TLC diyaar ah

D-Lys(tfa)-NCA (2)

La mid ah

N-[4-[(4R) -2,5-Dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoroacetamide Acetamide;
N-[4-[(4R) -2,5-dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoro-

Baakad gudaha ah

Caadi ahaan waxaa loo isticmaalaa in lagu xidho budada.Waxayna ka hortagi karaan qorraxda iyo biyaha inay xumaadaan.

Xirmooyinka gudaha 2
Xirmooyinka gudaha 1
Xirmooyinka gudaha 3

xirxirida dibadda

Kartoonka adag wuxuu ka ilaalin karaa alaabtaada inay shil galaan oo ay qoyaan.

Xirmooyinka dibadda 3
Xirmooyinka dibadda 2
Xirmooyinka dibadda 1

Codsiyada

  1. Wajiga adag ee Peptide Synthesis (SPPS): Gudaha SPPS, D-Lys(tfa) -NCA waxay u shaqeysaa sidii buundo si ay isugu xirto kooxda carboxyl ee hadhaaga amino acid ee hore iyo kooxda amino ee soo socota hadhaaga amino acid.Waxa ay samaysaa xidhid peptide ah kooxda karboksyl ee amino acid hore, si wax ku ool ah ugu darto amino acid cusub silsilad peptide koraya.
  1. Isku-darka Peptides ee Taxane Gaar ah: Isticmaalka D-Lys (tfa) -NCA, cilmi-baarayaashu waxay soo saari karaan peptides ka kooban D-lysine, taas oo faa'iido u leh barashada qaabka iyo shaqada borotiinka ama naqshadeynta daawooyinka peptide ee leh waxqabadyo bayooloji gaar ah.Maadaama habka stereochemical ee D- iyo L-amino acids ay saameyn ku yeelan karaan dhaqdhaqaaqa noolaha ee peptides, awooddani waa mid aad u qiimo badan.
  1. Synthesis Stereoselective: Sababtoo ah D-lysine waxay ka duwan tahay stereochemically L-lysine-ka caadiga ah, isticmaalka D-Lys (tfa) -NCA waxay soo bandhigi kartaa stereoselectivity ee isku-dhafka peptide.Tani waxay u oggolaaneysaa isku-dhafka peptides oo leh qaab-dhismeedka gaarka ah, kaas oo lagu baran karo saameynta ay ku leeyihiin dhaqdhaqaaqa noolaha.

alaabta la xidhiidha

L-Lys(tfa)-NCA Lys(Cbz)-NCA D-Lys(Cbz)-NCA Orn(Cbz)-NCA
Sar-NCA Gly-NCA L-Ala-NCA D-Ala-NCA

Sarraynta

1. Waxaanu ku siinaynaa habaynta alaabta aad u baahan tahay.
2. Tayo sare leh & qiimo tartan ah ayaa la bixin karaa.
3. Waxa aanu kuu balan qaadaynaa adeeg dabagal oo dhamaystiran.
4. Su'aalaha alaab-qeybiyaha iyo dukumentiyada farsamada waa la bixin karaa haddii la codsado ka dib marka la buuxiyo qadar go'an.
5. Adeegga iibka ka dib ama dammaanad qaadka weyn: Su'aashaada mid kasta ayaa lagu xallin doonaa sida ugu dhakhsaha badan.
6. Dhoofinta badeecadaha tartanka ku jira, sannad kastana tiro badan oo dibadda ah loo dhoofiyo.
7. Muunad bilaash ah oo la bixiyo si loo hubiyo tayada ka hor lacag bixin kasta.


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