13590-42-6 H-Asp(OBzl)-NCA

Cilmi-baarista biochemical:
Isku-darka peptide, H-Asp (OBzl) -NCA waxay u adeegtaa sidii dhisme muhiim ah oo loogu talagalay isku-dhafka silsiladaha peptide ee ka kooban taxanaha aspartic acid.
Kooxdeeda benzyl ester waxay u shaqeysaa sidii koox ilaalin ah, taas oo u oggolaanaysa soo-bandhigidda wax-ka-beddel kiimikaad gaar ah inta lagu jiro isku-dhafka silsiladda peptide, kaas oo markaa laga saari karo xaaladaha ku habboon si loo helo taxanaha aspartic acid ee la rabo.
Daraasadaha wax ka beddelka borotiinka ama peptide, H-Asp (OBzl) -NCA waxaa loo isticmaali karaa in lagu soo bandhigo isbeddello kiimiko ah oo gaar ah si loo baaro sida isbeddelladani u saameeyaan dhaqdhaqaaqa noolaha ama isdhexgalka molecules kale ee borotiinka ama peptide.
Helitaanka Dawada:
H-Asp (OBzl) -NCA waxay u adeegi kartaa sidii horudhac synthetic ama dhexdhexaadinta molecules daroogada, taas oo u oggolaanaysa soo bandhigida qaabab kiimiko oo gaar ah inta lagu jiro naqshadaynta daroogada si loo helo musharrixiinta daroogada ee waxqabadyada noolaha.
Iyada oo loo marayo falcelinta jajabyada daroogooyinka kale ama molecules bayooloji firfircoon, waxay fududeyn kartaa isku-darka daawooyinka peptide-ku-salaysan ama xeryahooda heterocyclic oo leh saameyno daaweyneed oo gaar ah.
Nidaamyada daahfurka daroogada, H-Asp(OBzl) -NCA waxa kale oo loo isticmaali karaa baadhista wax-soo-saarka sare leh iyo baaritaanka dhaqdhaqaaqa bayoolojiga si loo qiimeeyo hawlaha isku xigxiga peptide kala duwan ama musharaxiinta daroogada.
Warshadaha Daawooyinka:
Warshadaha dawooyinka, H-Asp (OBzl) -NCA waxay u adeegtaa sida walxo cayriin ah ama dhexdhexaad ah oo loogu talagalay soo saarista daawooyinka peptide-ka daweynta firfircoon.
Iyada oo loo marayo falcelinta uumiga leh asiidhyada amino-yada kale ama jajabyada daroogada, waxay fududayn kartaa isku-darka daawooyinka peptide ee leh hawlo bayooloji oo gaar ah, sida antibiyootiga, hormoonnada, xannibaadaha enzyme, iyo in ka badan.
Kooxda benzyl ester ee ku jirta qaabdhismeedkeeda waxay ilaalisaa karboksylic acid ee aspartic acid, taas oo gacan ka geysata xasilloonida iyo falcelinta silsiladda peptide inta lagu jiro isku-dhafka.