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109425-51-6 Fmoc-L-His(Trt)-OH

109425-51-6 Fmoc-L-His(Trt)-OH

Sharaxaad Gaaban:

Muuqashada Caddaan ilaa budo caddaan ah
MF C40H33N3O4
MW 619.71
daahirnimo 98+


Faahfaahinta Alaabta

Xaaladda gaadiidka
Waxay noqon kartaa heerkul caadi ah

Ku talin habka rarida
Hawada By Dhulka Badda

Xaaladda kaydinta:
Ku hay meel mugdi ah, jawi aan fiicneyn, heerkulka qolka

Nolosha shelf
Ilaa 2 sano

Dalabka ugu Yar:
1kg (gorgortanka)

shahaadoCOA, barta dhalaalka, SpecificRotation [α]D20                      

Waxaan kuu soo diri doonaa xog kasta oo aad rabto.Waxaad arki kartaa xogta ka hor tixraac ahaan.

Alaabta la habeeyey, waxaanu u dirnaa xogta ugu cusub ka dib markay soo baxaan.

D-Lys(tfa)-NCA (2)

La mid ah

N-Fmoc-N'-trityl-L-histidine

FMOC-N-IM-TRITYL-L-HISTIDINE

FMOC-HISTIDINE(1-TRT)-OH

FMOC-HIS(TRITYL)-OH

FMOC-HIS(TRT)

FMOC-HIS(TRT)-OH

FMOC-HIS(T-TRT)-OH

FMOC-HIS(1-TRT)-OH

FMOC-L-HIS(TRITYL)

Baakad gudaha ah

Inta badan waxaa loo isticmaalaa baakadaha budada.Waxay kuxirantahay shuruudaha macaamiishaSidaa darteed, noo sheeg dalabkaaga ka hor intaadan xirin haddii aad hayso codsiyo gaar ah.

Xirmooyinka gudaha 2
Xirmooyinka gudaha 1
Xirmooyinka gudaha 3

xirxirida dibadda

1kg ilaa 25kg Baakaynta dibadda waa adag tahay.Way adag tahay in la gooyo oo la dhaawaco.Waxay si fiican u ilaalin kartaa alaabtaada.

Xirmooyinka dibadda 3
Xirmooyinka dibadda 2
Xirmooyinka dibadda 1

Codsiyada

109425-51-6 Fmoc-L-His(Trt) -OH waxay iska leedahay derivatives L-histidine, taas oo ah amino acid lagama maarmaanka u ah aadanaha, marka la barbar dhigo amino acids kale, marka lagu daro qaar ka mid ah falcelin kiimikaad caadiga ah L-histidine sababtoo ah xaqeeda. Silsiladda dhinaca kooxda imidazole iyo diazobenzenesulfonic acid waxay samayn karaan dhisme casaan-brown ah, taas oo ah, falcelinta Pauly (Pauly).

109425-51-6 Fmoc-L-His (Trt) -OH sidoo kale waxay noqon kartaa mid ka mid ah Triptorelin Acetate Intermediates.Triptorelin, decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly -NH2), waa gonadotropin-sii daynta hoormoonka agonist (GnRH agonist) oo loo isticmaalo sidii acetate ama cusbada pamoate.Iyadoo keenaysa kicinta joogtada ah ee pituitary, waxay hoos u dhigtaa dheecaanka pituitary ee gonadotropins luteining hormone (LH) iyo hoormoonka kicinta follicle (FSH).Sida agonistayaasha kale ee GnRH, triptorelin waxaa loo isticmaali karaa daawaynta kansarka ka jawaaba hoormoonka sida kansarka qanjirka 'prostate' ama kansarka naasaha, qaan-gaarnimada hore, xaaladaha estrogen-ku-tiirsan (sida endometriosis ama fibroids uterine), iyo taranka la caawiyay.Waxa kale oo loo isticmaalaa daawayn ahaan xaaladaha dysphoria jinsiga.

Inta lagu jiro daawaynta kansarka qanjirka 'prostate' waxay keentaa kor u kaca testosterone (kor u kaca heerka hore ee testosterone), oo loo yaqaan saamaynta ololka.Ragga hoos u dhigista heerarka testosterone serum ee kala duwanaanshaha sida caadiga ah la arko ka dib qalliinka qalliinka waxay dhacdaa qiyaastii laba ilaa afar toddobaad ka dib bilawga daaweynta.Taas bedelkeeda, gonadotropin-hormoonka antagonistayaasha ma keenaan qalliin, laakiin hoos u dhac lama filaan ah oo heerarka testosterone.

alaabta la xidhiidha

L-His-OH D-His-OH L-His(trt)-OH D-His(trt)-OH
Boc-L-His-OH Boc-L-His(trt)-OH Boc-D-His(trt)-OH Fmoc-L-His-OH
Fmoc-D-His(Trt)-OH Boc-His(Trt)-Gly-OH Boc-L-His(Trt)-Aib-OH Fmoc-His(Mmt)-OH

Maxaa noo doora

1. Ku saabsan MOQ-ga: Waxaan ku hagaajin karnaa si waafaqsan shuruudahaaga.
2. Ku saabsan muunada: Muunadu waxay u baahan tahay kharashka muunada, taas oo noqon karta xamuul si loo qaado ama aad horay noogu sii bixin karto.
3. Aqoon-is-weydaarsiga caaryada, waxaa loo habeyn karaa iyadoo loo eegayo tirada moodooyinka.
4. Waxaan bixinaa adeegga ugu fiican.Koox iib ah oo khibrad leh ayaa mar horeba adiga kuu shaqaynaysa.
5. Ku saabsan wax-is-weydaarsiga: Fadlan ii-mayl u dir ama ila sheekee marka ay kugu habboon tahay.


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